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Chair's Message

Wendy A. Wells, MD

The Department of Pathology and Laboratory Medicine, affiliated with Dartmouth College's Geisel School of Medicine, comprises nationally and internationally recognized Faculty and staff who provide comprehensive, sub-specialty surgical pathology and laboratory medicine expertise to the academic medical center in Lebanon, NH and regionally throughout the Dartmouth-Hitchcock Healthcare system.

The Department has three translational research programs of national distinction:

  • The Laboratory for Clinical Genomics and Advanced Technologies (CGAT)
  • The Cellular Therapy Center (CTC)
  • The Cell Labeling Laboratory (CLL)

We also provide a state-of-the-art Pathology Shared Resource that provides an array of translational laboratory services to collaborators at the NCI-designated Norris Cotton Cancer Center (NCCC), Dartmouth's Geisel School of Medicine and biomedical engineers at Dartmouth's Thayer School of Engineering.

Our externally funded programs have four focuses:

  1. Biomarker discovery and validation to implement new technologies clinically and refine disease classifications (examples: liquid biopsy, digital spatial profiling, nanopore sequencing, quantitative multiplexed IHC, CRISPR, miRNA profiling, organoids).
  2. Computational, augmented pathology to implement and commercialize enhanced algorithms for faster and more accurate diagnoses (examples: digital image technology, artificial intelligence, data warehousing and mining).
  3. Clinical Trials to assess new technologies, practices and companion diagnostics (examples: NCI MATCH funding, cellular therapy, apheresis, transfusion medicine.
  4. Population Health studies in Pathology, regionally and globally.

The Department has completed major infrastructure improvements in the last 5 years and retains physical connectivity between almost all divisions of Surgical Pathology and Laboratory Medicine. LEAN process improvement tools have been implemented lab-wide to optimize efficiency by eliminating waste, reducing cost per test and improving test result turnaround-time. The physical space has been renovated to reflect the improved workflow and to optimize equipment layout.

All Faculty participate in the teaching and mentoring of our Pathology Residents and Fellows (in Hematopathology, Cytopathology, Transfusion Medicine and Dermatopathology fellowships). All Faculty also teach medical students from the Geisel School of Medicine at Dartmouth, throughout their four years, as part of the new Pathology Longitudinal Course curriculum. We provide a post-sophomore or post-junior fellowship year for up to two medical students every year in the Department and global health initiatives in the Department have taken Faculty to Honduras, Kosovo, Uganda and Peru. Opportunities to complete Master's degrees in Public Health, Outcomes research and Health Care Delivery science at The Dartmouth Institute for Health Policy and Clinical Practice are also available to the Faculty.

Wendy A. Wells, MD

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